Biophysics of Membrane Proteins
My primary research focuses on the biophysical mechanisms of membrane proteins, particularly channels and secondary active transporters. I especially like to use structural techniques (CryoEM and X-ray) to describe the physical properties of each protein, and the effects of disease mutations.
Sauer et al. Structure and inhibition mechanism of the human citrate transporter NaCT. Nature (2021)
Computational Biology
I also have an interest in computational biology, especially as it relates to structural biology, thermoadaptation, and reverse ecology. Of particular interest is the application of computational tools to structural biology, or aiding the interpretation of structural and biochemical results.